SECTION 310:550-5-2. Technique for filter paper sample collection and pulse oximetry screening

(a)   Filter paper sample collection.

(1)   Specimens obtained with a Newborn Screening Form Kit should be collected in accordance with the standard for Blood Collection on Filter Paper for Newborn Screening Programs, NBS01-A6, Sixth Edition, as adopted and published by the Clinical and Laboratory Standards Institute on July 31, 2013, or most recent version. Failure to follow these methods of blood collection may cause inaccurate results and require repeat specimens.

(2)   Submitters are responsible for submitting a Satisfactory Newborn Screening Specimen.

(b)   Pulse oximetry screening.

(1)   Pulse oximetry screening. Pulse oximetry screening will be performed utilizing hospital protocol. A recommended protocol is provided by the program.

(2)   Authorized provider. An authorized health care provider shall perform the pulse oximetry screening.

(3)   Newborn Infants Receiving Routine Care.

(A)   The birthing facility or nurse shall:

(i)   Perform pulse oximetry screening on the newborn Infant between twenty-four (24) hours and forty-eight(48) hours of life; or

(ii)   If unable to perform the pulse oximetry screening, schedule the infant to be screened at the facility between twenty-four (24) hours and forty- eight (48) hours of life; or

(iii)   Notify the infant's physician if screening was not performed.

(B)   If the newborn infant is discharged from a facility after twelve (12) hours of life but before twenty-four (24) hours of life, the birthing facility shall perform pulse oximetry screening as late as is practical before the newborn infant is discharged from the birthing facility and shall notify the infant's physician of the early screening.

(C)   If the infant is discharged before twelve (12) hours of life, the birthing facility shall perform the pulse oximetry screening between twenty-four (24) hours and forty-eight (48) hours of life.

(4)   Newborn infants in Special Care or Intensive Care. Birthing facilities shall perform pulse oximetry screening on infants prior to discharge utilizing the protocol recommended by the program, unless the infant has an identified congenital heart defect or has an echocardiogram done. Continuous pulse oximetry monitoring may not be substituted for CCHD screening.

(5)   Circumstances Where Pulse Oximetry Screening is not Indicated. Document on NBS filter paper the pulse oximetry screening was not performed. There may be instances where screening for CCHD is not indicated, including but not limited to instances where:

(A)   The newborn infant's clinical evaluation to date has included an echocardiogram which ruled out CCHD; or

(B)   The newborn infant has confirmed CCHD based on prenatal or postnatal testing.

[Source: Amended at 8 Ok Reg 3115, eff 7-12-91 (emergency); Amended at 9 Ok Reg 1475, eff 5-1-92; Amended at 12 Ok Reg 41, eff 10-5-94; Amended at 12 Ok Reg 1685, eff 6-12-95; Amended at 21 Ok Reg 1286, eff 5-27-04; Amended at 31 Ok Reg 1596, eff 9-12-14; Amended at 36 Ok Reg 1688, eff 9-13-19]